Dr. Alexandra Weyrich

Scientist

Head of Wildlife Epigenetics

Department of Evolutionary Genetics

Tel: 0049 (0) 30 5168 - 334
E-Mail: weyrich@izw-berlin.de

© Photo: Stefan Bernhardt
Deutsches Zentrum für intergrative Biodiversitätsforschung, Halle-Jena-Leipzig (iDiv)
Projects
Research interests

- Epigenetic mechanims and regulation of gene expression

- Epigenetics of social systems

- Environmental factors

- Thermoregulation

Selected publications

Grunau C and Weyrich A (2024): L`épigenétique dans l`évolution, Chap. 11, Livre Épigénétique en écologie et évolution, ISTE editions. doi:10.51926/ISTE.9216.ch11

Vullioud C, Benhaiem S, Meneghini D, Szyf M, Shao Y, Hofer H, East M, Fickel J, Weyrich A (2024) Commun Biol 7, 313. doi.org/10.1038/s42003-024-05926-y

Weyrich A, Guerrero-Altamirano TP, Yasar S, Czirják GA, Wachter B, Fickel J (2022) First Steps towards the Development of Epigenetic Biomarkers in Female Cheetahs, Life 2022, 12(6), 920. doi.org/10.3390/life12060920

Westbury MV, Le Duc D, Duchêne DA, Krishnan A, Prost S, Rutschmann S, Grau JH, Dalen L, Weyrich A, Norén K, Werdelin L, Dalerum F, Schöneberg T, Hofreiter M (2021): Ecological specialisation and evolutionary reticulation in extant Hyaenidae. MOL BIOL EVOL msab055. doi:10.1093/molbev/msab055

Li K*, Zhang S*, Song X*, Weyrich A*, Wang Y, Liu X, Wan N, Liu J, Lövy M, Cui H, Frenkel V, Titievsky A, Panov J, Brodsky L, Nevo E (2020): Genome evolution of blind subterranean mole rats: Adaptive peripatric versus sympatric speciation. PROC NATL ACAD SCI USA 117, 32499–32508. *shared first author. doi:10.1073/pnas.2018123117

Weyrich A, Yasar S, Lenz D, Fickel J (2020): Tissue‑specific epigenetic inheritance after paternal heat exposure in male wild guinea pigs. MAMM GENOME 31, 157–169. Invited to special issue. doi:10.1007/s00335-020-09832-6

Guerrero TP, Fickel J, Benhaiem S, Weyrich A (2020): Epigenomics and gene regulation in mammalian social systems. CURR ZOOL 66, 307–319. Invited to special issue on “Social behavior and evolution in the omics era”. doi:10.1093/cz/zoaa005

Weyrich A, Lenz D, Fickel J (2019): Environmental change-dependent transgenerational epigenetic response. GENES 10, 4. Invited to special issue on “Epigenetics and Adaptation”. doi: 10.3390/genes10010004

Weyrich A, Jeschek M, Schrapers KT, Lenz D, Chung H, Rübensam K, Yasar S, Schneemann M, Ortman S, Jewgenow K, Fickel J (2018): Diet changes alter paternally inherited epigenetic pattern in male wild guinea pigs. ENVIRON EPIG 4(2): dvy011. doi:10.1093/eep/dvy011

Weyrich A, Benz S, Karl S, Jeschek M, Jewgenow K, Fickel J (2016): Paternal heat exposure causes DNA methylation and gene expression changes of Stat3 in wild guinea pig sons. ECOL EVOL 6, 2657-2666. doi: 10.1002/ece3.1993

Weyrich A, Lenz D, Jeschek M, Chung TH, Rübensam K, Göritz K, Jewgenow K, Fickel J (2016): Paternal intergenerational epigenetic response to heat exposure in male wild guinea pigs. MOL ECOL 25: 1729-1740. Invited to special issue on “Epigenetic Studies in Ecology and Evolution”. doi:10.1111/mec.13494

Weyrich A, Schüllermann T, Heeger F, Jeschek M, Mazzoni C.J., Chen W, Schumann K, Fickel J (2014): Whole genome sequencing and methylome analysis of the wild guinea pig. BMC GENOMICS 15(1):1036. doi:10.1186/1471-2164-15-1036

Weyrich A, Tang X, Xu G, Schrattenholz A, Hunzinger C, Hennig W (2008): Mammalian DNMTs in the male germ line DNA of Drosophila. BIOCHEM CELL BIOL 86: 380-385. doi:10.1139/O08-096

Last updated on February, 25th 2025