Dr. Alexandra Weyrich

Scientist
Head of Wildlife Epigenetics
Department of Evolutionary Genetics
© Photo: Stefan Bernhardt
Deutsches Zentrum für intergrative Biodiversitätsforschung, Halle-Jena-Leipzig (iDiv)
Epigenetic stability and plasticity of social environmental effects in spotted hyenas
Comparative environmental epigenomics in wildlife
Behaviour, ecology and health of spotted hyenas in the Serengeti National Park
Good reproduction and health status in a genetically monomorphic species, the cheetah
- Epigenetic mechanims and regulation of gene expression
- Epigenetics of social systems
- Environmental factors
- Thermoregulation
Grunau C and Weyrich A (2024): L`épigenétique dans l`évolution, Chap. 11, Livre Épigénétique en écologie et évolution, ISTE editions. doi:10.51926/ISTE.9216.ch11
Vullioud C, Benhaiem S, Meneghini D, Szyf M, Shao Y, Hofer H, East M, Fickel J, Weyrich A (2024) Commun Biol 7, 313. doi.org/10.1038/s42003-024-05926-y
Weyrich A, Guerrero-Altamirano TP, Yasar S, Czirják GA, Wachter B, Fickel J (2022) First Steps towards the Development of Epigenetic Biomarkers in Female Cheetahs, Life 2022, 12(6), 920. doi.org/10.3390/life12060920
Westbury MV, Le Duc D, Duchêne DA, Krishnan A, Prost S, Rutschmann S, Grau JH, Dalen L, Weyrich A, Norén K, Werdelin L, Dalerum F, Schöneberg T, Hofreiter M (2021): Ecological specialisation and evolutionary reticulation in extant Hyaenidae. MOL BIOL EVOL msab055. doi:10.1093/molbev/msab055
Li K*, Zhang S*, Song X*, Weyrich A*, Wang Y, Liu X, Wan N, Liu J, Lövy M, Cui H, Frenkel V, Titievsky A, Panov J, Brodsky L, Nevo E (2020): Genome evolution of blind subterranean mole rats: Adaptive peripatric versus sympatric speciation. PROC NATL ACAD SCI USA 117, 32499–32508. *shared first author. doi:10.1073/pnas.2018123117
Weyrich A, Yasar S, Lenz D, Fickel J (2020): Tissue‑specific epigenetic inheritance after paternal heat exposure in male wild guinea pigs. MAMM GENOME 31, 157–169. Invited to special issue. doi:10.1007/s00335-020-09832-6
Guerrero TP, Fickel J, Benhaiem S, Weyrich A (2020): Epigenomics and gene regulation in mammalian social systems. CURR ZOOL 66, 307–319. Invited to special issue on “Social behavior and evolution in the omics era”. doi:10.1093/cz/zoaa005
Weyrich A, Lenz D, Fickel J (2019): Environmental change-dependent transgenerational epigenetic response. GENES 10, 4. Invited to special issue on “Epigenetics and Adaptation”. doi: 10.3390/genes10010004
Weyrich A, Jeschek M, Schrapers KT, Lenz D, Chung H, Rübensam K, Yasar S, Schneemann M, Ortman S, Jewgenow K, Fickel J (2018): Diet changes alter paternally inherited epigenetic pattern in male wild guinea pigs. ENVIRON EPIG 4(2): dvy011. doi:10.1093/eep/dvy011
Weyrich A, Benz S, Karl S, Jeschek M, Jewgenow K, Fickel J (2016): Paternal heat exposure causes DNA methylation and gene expression changes of Stat3 in wild guinea pig sons. ECOL EVOL 6, 2657-2666. doi: 10.1002/ece3.1993
Weyrich A, Lenz D, Jeschek M, Chung TH, Rübensam K, Göritz K, Jewgenow K, Fickel J (2016): Paternal intergenerational epigenetic response to heat exposure in male wild guinea pigs. MOL ECOL 25: 1729-1740. Invited to special issue on “Epigenetic Studies in Ecology and Evolution”. doi:10.1111/mec.13494
Weyrich A, Schüllermann T, Heeger F, Jeschek M, Mazzoni C.J., Chen W, Schumann K, Fickel J (2014): Whole genome sequencing and methylome analysis of the wild guinea pig. BMC GENOMICS 15(1):1036. doi:10.1186/1471-2164-15-1036
Weyrich A, Tang X, Xu G, Schrattenholz A, Hunzinger C, Hennig W (2008): Mammalian DNMTs in the male germ line DNA of Drosophila. BIOCHEM CELL BIOL 86: 380-385. doi:10.1139/O08-096
Last updated on February, 25th 2025